There are three main types of FDA-approved medication categories:
1. Cholinesterase Inhibitors
Inhibits the enzyme acetylcholinesterase (which breaks down acetylcholine). Acetylcholine plays an important role in memory and learning. Goal is to treat symptoms related to memory, thinking, language, judgment, and other thought processes.
Common side effects:
2. Glutamate Regulator
Regulates the activity of glutamate. Glutamate plays an important role in helping the brain process information. Goal is to improve memory, attention, reason, language, and ability to perform simple tasks.
Common Side Effects:
3. Cholinesterase Inhibitor + Glutamate Regulator
Combination drug.
Common Side Effects:
Important Notes:
There is no evidence that any of the above medications prevent or slow neurodegeneration in people with Alzheimer’s disease. There are solely for symptom management.
There are more potential side effects than have been listed for the above medications.
Please talk to you or your partner’s doctor for specific advice and recommendations regarding any medications.
AD = Alzheimer's Disease
PDD = Parkinson's Disease Dementia
To learn more about these FDA-approved medications including Aduhelm and Leqembi check out this link:
https://www.alz.org/alzheimers-dementia/treatments/medications-for-memory
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